Simon Mignolet and Loris Karius both miss out as Danny Ward starts the game instead with James Milner returning from injury and Ragnar Klavan, Jon Flanagan and Joe Gomez completing the backline.
Adam Lallana starts alongside Gini Wijnaldum with Emre Can who retains his place from the last game.
Sadio Mane also retains his place in the side, with Ben Woodburn and Dominic Solanke starting for the Reds front 3.
Coutinho, Salah, Moreno and Dejan Lovren miss the game tonight as they have been given some time off.
Henderson, Firmino and Joel Matip are in Jurgen Klopp's Arsenal for the game.